Verismo Therapeutics

Verismo Therapeutics

The team that invented the first FDA-approved CAR-T therapy is back to revolutionize the space with the KIR-CAR.

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Industry
Biotechnology Research
Company size
32 people
Headquarters
Philadelphia, Pennsylvania
Founded
2020
Type
Privately Held
Total funding
$72.2M

Verismo Therapeutics is pioneering the development of novel chimeric antigen receptors (CARs) that enhance T-cell-based cellular immunotherapy for cancer, especially non-hematologic malignancies with few effective therapeutic options. Verismo Therapeutic’s core technology is built upon CARs that are uniquely engineered to more realistically reflect the natural multichain design of killer immunoglobulin-like receptors (KIRs), an important family of immunologic receptors used by T cells and NK cells. Preclinical studies show that SynKIR™-T cells, created by introducing these KIR-based CARs (KIR-CARs) into T cells, more effectively eliminate aggressive tumors in vivo when compared with T cells bearing traditional 2nd generation CAR designs found in current FDA approved CAR-T cell therapies.

CAR-T Cell Therapy Solid Tumor Immuno-Oncology and KIR-CAR Platform

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